In past years, thiamine has been prescribed to patients with heart failure to help ease symptoms and promote the delay in the progression of the disease. Thiamine is an essential vitamin that aids in the synthesis of ATP and energy production. It has been shown that patients with heart failure tend to have unbalanced energy consumption levels. The intent of prescribing thiamine has been to balance energy consumption as micronutrient imbalance can lead to decreased myocardial energy production. Many studies have denied the support of thiamine supplementation; however, it can help promote cardiac function and improve symptoms in patients with heart failure.